Madrid Declaration on Ozone Therapy (2nd. edition)

1. THERAPEUTIC BASIS
2. OZONE (O3X). BASIC PRINCIPLES
2.1 Contraindications
2.2 Interactions with ozone
2.3 Adverse effects
2.3.1 Level 1 Mild
2.3.2 Grade 2 Moderate
2.3.3 Grade 3 Severo
2.3.4 Grade 4
2.3.5 Grade 5
2.4 Toxicity
2.5 Pediatric Dose rectal insufflation
3. MAIN ROUTES OF APPLICATION
3.1 Application Paths recommended
3.1.1 Greater Autohemoterapia (AHTMayor)
3.1.2 Lower Autohemoterapia (AHTMenor)
3.1.3 Infiltration intramuscular and intra-articular
3.1.4 Paravertebral Infiltration
3.1.5 Herniated
3.1.6 Infiltration intradiscal
3.1.7 Infiltration sacral hiatus flow / Epidural transluminal
3.1.8 Infiltration intraforaminal
3.1.9 Treatment intra-articular
3.1.10 Glove technique (Technique Subcutaneous emphysema)
3.1.11 Gasification bag
3.1.12 Technical subcutaneous
3.1.13 Suction pads with ozone
3.1.14 Insufflation in fistulas
3.1.15 Ophthalmology
3.1.16 Vaginal insufflation
3.1.17 Insufflation vesico-urethral
3.1.18 Otic insufflation
3.1.19 Intratonsilar Infiltration
3.1.20 Micro doses of ozone trigger points and acupuncture
3.1.21 Application subcutaneous
3.1.22 Ozonated saline
3.1.23 Extracorporeal ozonation (EBOO)
3.1.24 Rectal insufflation
3.2 Application Paths not recommended be unsafe
3.2.1 Ozone direct IV injection
3.2.2 Direct intra-arterial injection
3.3 Application Paths prohibited
3.4 Application Paths that have not received full consensus
3.4.1 Intra-articular injection of ozonated water
3.4.2 Intra-peritoneal insufflation

3.5 Essential requirements
4. PATHOLOGIES MORE APPROPRIATE TO BE TREATED WITH OZONE
4.1 Diseases Level A
Disease level 4.2 B
4.3 Diseases C level
5. GENERAL RULES OF TREATMENT
6. BASIC RULES TO CONDUCT TRAINING COURSES OZONOTERAPIA
ADDENDUM A. Clinical Applications of ozone in dentistry
ADDENDUM B. Mutagenesis, toxicity and adverse reactions in ozonoterapia
REFERENCES